Their research has been published in the Proceedings of the National Academy of Science. Thousands of web pages all over the world are now carrying this story and a mention of our funding is showing up in them, over and over!
Imagine seeing our own Alzheimer’s Art Quilt Initiative listed right next to the National Institutes of Health on one of the many thousands of web sites carrying this story on the latest Alzheimer's discovery!
In March of this year, the Alzheimer’s Art Quilt Initiative awarded a $30,000 grant to the University of Michigan for research under the direction of assistant professor Dr. Mi Hee Lim for research she has been doing with lab members Jung-Suk Choi and Joseph Braymer regarding molecular tools that both grab metal ions and interact with amyloid-beta tangles in Alzheimer's victims brains.
AAQI has now awarded six grants since we began making, donating, and raising research monies with quilts and this was the third of those six awarded so far. Ami and her support team not only brought the check for our earned research monies but she also brought quilts to show the researchers, as well. Just picture that amazing scene.....Ami and her support staff showing our quilts as they described how we make them, donate them, and auction them off to raise the money for the check that Ami then handed over to them! What a wonderful and amazing thing!
Because of our funding, Dr Lim and her team were able to create new molecular tools that show promise for cleansing the brain of amyloid plaques. These plaques, a hallmark of Alzheimer’s disease, are clumps of misfolded proteins thought to cause cell death leading to devastating memory loss and cognitive decline. Finding ways to cross through the blood brain barrier is something I have been reading about for years and here this team has worked out a means and a method that might significantly alter Alzheimer's research from now on!
The researchers went on to show that in solutions with or without living cells, the molecules were able to regulate copper-induced amyloid-beta aggregation, not only disrupting the formation of clumps, but also breaking up clumps that already had formed.
This is just one amazing step towards a possible cure, but it's a promising one!
As someone who has a very great chance of getting Alzheimer's myself...with 15 immediate family members having had or my mother now currently having this horrible disease....everything that AAQI does, every word that Ami Simms writes or says in a press release means the world to me and I have shared that with her repeatedly. She and all of the researchers and all who care and take that caring and do something positive with it...they are my heroes.
If any one of you, who loved your own mother, your own father, your aunts or yours uncles, your husbands, or sisters or brothers, had to watch what happens to them...first their memory, then their body...limb by limb, organ by organ, until they no longer have control over anything anymore...trust me, you would be as passionate as I am.
Never underestimate the power of quilts, quilters, and quilting! We are making a difference!
Alzheimer's Illustrated: From Heartbreak to Hope
I support the Alzheimer's Art Quilts Initiative
and moderate the AAQI Liberated Quilters Challenge
Please help me by joining in and making small 4" x 6" or 9" x 12" art quilts for this cause.
Link to this story:
Quilters Finance New Alzheimer's Discovery
Unraveling Alzheimer’s: Simple small molecules could untangle complex disease
Quilters Finance New Alzheimer’s Discovery
Ongoing Liberated Quilting Challenge: new quilts added in
Liberated Quilting Challenge
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Michele Bilyeu quilts for AAQI..the Alzheimer's Art Quilt Initiative. Won't you please join us? :)
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